Caffeine is a naturally occurring purine alkaloid that belongs to the methylxanthine class of compounds extracted from the seeds, leaves, and fruits of certain plants like Coffea arabica, Camellia sinensis, Theobroma cacao, and Cola acuminata. It can also be synthesized from urea and cyanoacetic acid. Caffeine exhibits eugeroic, analeptic, cardiac stimulant, diuretic, ergogenic, and nootropic properties, making it effective in pharmaceutical and nutraceutical uses. It is widely recognized for its inclusion in energy-boosting beverages, over-the-counter pain relievers, and sports nutrition products due to its ergogenic and nootropic benefits.
Caffeine works primarily as an adenosine receptor antagonist by blocking adenosine, a neurotransmitter that promotes relaxation and sleepiness. It also stimulates the central nervous system,leading to the release of neurotransmitters like adenosine, dopamine, and norepinephrine. This results in enhanced alertness, wakefulness, and improved cognitive performance. Caffeine also promotes diuresis, helping the body eliminate extra salt and water trough urination. Additionally, caffeine stimulates thermogenesis and lipolysis, aiding in weight management and exercise endurance.
CAS No.:58-08-2
Synonyms: 1,3,7-Trimethylxanthine, Caffedrine, Caffeine, Coffeinum N, Coffeinum Purrum, Dexitac, Durvitan
| Physical Properties | |
| Chemical formula | C8H10N4O2 |
| IUPAC Name | 1,3,7-trimethylpurine-2,6-dione |
| Molecular weight | 194.19 g/mol |
| Solubility | Soluble in DMSO, dimethyl formamide, and dichloromethane Sparingly soluble in water Moderately soluble in ethanol |
| Half-life | 5-6 hrs |
| Chemical Properties | |
| Color | White |
| Appearance | White glistening needles or Powder form |
| Density | 1.23 g/cm³ |
| pH | 6.9 |
| Odor | Odorless |
| pka | 14 at 25 °C |
| Pictograms : |  |
| Hazard Statements : | H302: Harmful if swallowed |
| Precautionary statements : | P264 Wash skin thoroughly after handling. P270 Do not eat, drink, or smoke when using this product. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P330 Rinse mouth. P501 Dispose of contents/ container to an approved waste disposal plant. |
Caffeine is a naturally occurring purine alkaloid that belongs to the methylxanthine class of compounds extracted from the seeds, leaves, and fruits of certain plants like Coffea arabica, Camellia sinensis, Theobroma cacao, and Cola acuminata. It can also be synthesized from urea and cyanoacetic acid. Caffeine exhibits eugeroic, analeptic, cardiac stimulant, diuretic, ergogenic, and nootropic properties, making it effective in pharmaceutical and nutraceutical uses. It is widely recognized for its inclusion in energy-boosting beverages, over-the-counter pain relievers, and sports nutrition products due to its ergogenic and nootropic benefits.
Caffeine works primarily as an adenosine receptor antagonist by blocking adenosine, a neurotransmitter that promotes relaxation and sleepiness. It also stimulates the central nervous system,leading to the release of neurotransmitters like adenosine, dopamine, and norepinephrine. This results in enhanced alertness, wakefulness, and improved cognitive performance. Caffeine also promotes diuresis, helping the body eliminate extra salt and water trough urination. Additionally, caffeine stimulates thermogenesis and lipolysis, aiding in weight management and exercise endurance.
CAS No.:58-08-2
Synonyms: 1,3,7-Trimethylxanthine, Caffedrine, Caffeine, Coffeinum N, Coffeinum Purrum, Dexitac, Durvitan
| Physical Properties | |
| Chemical formula | C8H10N4O2 |
| IUPAC Name | 1,3,7-trimethylpurine-2,6-dione |
| Molecular weight | 194.19 g/mol |
| Solubility | Soluble in DMSO, dimethyl formamide, and dichloromethane Sparingly soluble in water Moderately soluble in ethanol |
| Half-life | 5-6 hrs |
| Chemical Properties | |
| Color | White |
| Appearance | White glistening needles or Powder form |
| Density | 1.23 g/cm³ |
| pH | 6.9 |
| Odor | Odorless |
| pka | 14 at 25 °C |
| Pictograms : | |
| Hazard Statements : | H302: Harmful if swallowed |
| Precautionary statements : | P264 Wash skin thoroughly after handling. P270 Do not eat, drink, or smoke when using this product. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P330 Rinse mouth. P501 Dispose of contents/ container to an approved waste disposal plant. |
Green tea naturally contains caffeine, but in smaller amounts than coffee. A standard cup of green tea contains 30 mg to 50 mg of caffeine.
Caffeine pills are safe when used under the recommended limits, typically not more than 200 mg per dose and 400 mg per day. However, it is advisable to consult with a health expert before consuming.
Caffeine stimulates various hormones inside the body, such as adenosine and dopamine, and boosts energy, increases alertness, and improves focus.
Caffeine can lead to increased restlessness and anxiety. While it may help improve daytime alertness in people with sleep apnea, it can also disrupt sleep if overused.
Caffeine stimulates the central nervous system and can temporarily raise blood pressure. It acts as a vasoconstrictor in the brain, which may reduce headaches, and as a vasodilator in other parts of the body, improving circulation.
Over consumption of caffeine may lead to increased heart rate, anxiety, restlessness, insomnia, headaches, dependence, and digestive issues.
