Anthrone is a tricyclic aromatic ketone and a derivative of anthracene, chemically classified as 9,10-dihydroanthracene carrying an oxo group at the C-9 position. It exists in tautomeric equilibrium with 9-anthrol and has been reported to possess radical scavenging properties. Anthrone occurs naturally as the structural backbone of several anthrone derivatives found in medicinal plants and has also been identified in certain microorganisms. Under acidic conditions, it readily reacts with carbohydrates to form a characteristic colored complex, a property that has made it a well-recognized analytical reagent in biochemical analysis.
CAS No.: 90-44-8Â
Synonyms: 9(10H)-Anthracenone, Carbothrone, anthracen-9(10H)-one
| Physical Properties | |
| Chemical formula | C14H10O |
| IUPAC Name | 10H-anthracen-9-one |
| Molecular weight | 194.23Â g/mol |
| Solubility | Insoluble in water |
| Appearance | Yellow crystalline powder |
| Storage | Store at room temperature |
| Chemical Properties | |
| Color | Yellow crystalline |
| Physical State (at 20 °C) | Solid |
| Melting Point | 155 °C to 158 °C |
| Boiling Point | 721 °C |
| Odor | Light characteristic odor |
| Pictograms : |  |
| Hazard Statements : | H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation |
| Precautionary statements : | P261: Avoid breathing dust P280: Wear protective gloves/eye protection P302+P352: IF ON SKIN: Wash with plenty of water. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing  |
Anthrone is a tricyclic aromatic ketone and a derivative of anthracene, chemically classified as 9,10-dihydroanthracene carrying an oxo group at the C-9 position. It exists in tautomeric equilibrium with 9-anthrol and has been reported to possess radical scavenging properties. Anthrone occurs naturally as the structural backbone of several anthrone derivatives found in medicinal plants and has also been identified in certain microorganisms. Under acidic conditions, it readily reacts with carbohydrates to form a characteristic colored complex, a property that has made it a well-recognized analytical reagent in biochemical analysis.
CAS No.: 90-44-8Â
Synonyms: 9(10H)-Anthracenone, Carbothrone, anthracen-9(10H)-one
| Physical Properties | |
| Chemical formula | C14H10O |
| IUPAC Name | 10H-anthracen-9-one |
| Molecular weight | 194.23Â g/mol |
| Solubility | Insoluble in water |
| Appearance | Yellow crystalline powder |
| Storage | Store at room temperature |
| Chemical Properties | |
| Color | Yellow crystalline |
| Physical State (at 20 °C) | Solid |
| Melting Point | 155 °C to 158 °C |
| Boiling Point | 721 °C |
| Odor | Light characteristic odor |
| Pictograms : | |
| Hazard Statements : | H315: Causes skin irritation H319: Causes serious eye irritation H335: May cause respiratory irritation |
| Precautionary statements : | P261: Avoid breathing dust P280: Wear protective gloves/eye protection P302+P352: IF ON SKIN: Wash with plenty of water. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing  |
Anthrone is primarily used as a reagent for the colorimetric determination of carbohydrates. It is widely used in cellulose, starch, and total sugar assays, as well as in the quantitative analysis of sugars in biological samples and plant extracts.
The Anthrone reaction usually gives a blue-green or green color under normal test conditions. Certain specific analytes may produce color variations based on the composition of the sample and reaction conditions.
Anthrone and anthracene are different compounds. Anthracene is a polycyclic aromatic hydrocarbon and does not have a carbonyl group, while Anthrone is an oxygen-containing ketone derivative of anthracene
The Anthrone assay consists of the reaction of carbohydrates with anthrone reagent in concentrated sulphuric acid. Carbohydrates were dehydrated to form furfural derivatives which react with anthrone to produce a colored complex that was measured spectrophotometrically.
Anthrone is generally prepared by the reduction of anthraquinone with reducing agents such as tin or copper. It can also be synthesized through the cyclization of o-benzylbenzoic acid under suitable reaction conditions.
