What is Selenium Sulfide?
Selenium sulfide also known as Selenium disulfide is an anti-fungal agent with keratolytic properties. It’s a chemical compound that helps in curing various skin infections including fungal & yeast infections, by inhibiting the growth of these organisms.

CAS No.: 7488-56-4
Synonyms: selenosulfide, Selenium sulphide, Selensulfid, Selenium sulfide red powder, selenenyl sulfide, Selenium Sulfide USP.
Properties of Selenium Sulfide
| Physical Properties | |
| Chemical formula | SSe |
| IUPAC Name | Selenium disulfide |
| Molecular weight | 111.04 g/mol |
| Solubility | In carbon disulfide |
| Insoluble | In H2O & Organic solvents/td> |
| Density | 3.0g/cm3 at 32°C |
| Chemical Properties | |
| Color | Bright orange or yellow |
| State | Powder |
| Melting point | 231.9°F (111°C) |
| Boiling Point | 224-246°F |
| Specific gravity | 3.056 at 32°F |
Applications of Selenium Sulfide
- Medical Diagnosis:
Seborrheic Dermatitis – Selenium sulfide 2.5% shampoo works by reducing the production of sebum and inhibits the growth of fungi, improving the symptoms of seborrheic dermatitis and dandruff.Yeast dermatitis – Selenium sulfide is effective in treating yeast dermatitis by inhibiting the growth of yeast on the skin. It reduces symptoms like redness, itching, and flaking, providing relief and improving skin condition with regular use.
Tinea versicolor – Selenium sulfide usp 2.5 lotion helps in the treatment of tinea versicolor, a fungal infection that causes discolored patches on the skin, by reducing fungal growth it helps to restore the skin’s normal color and texture with consistent application.
Jock Itch – Selenium sulfide can be used to treat Jock itch, a fungal infection in the groin area as it inhibits the fungal growth and relieves symptoms like itching and irritation.
- Veterinary Medicine: Selenium sulfide is used in veterinary medicine for the primary treatment of fungal infections like ringworm in animals. It helps to reduce itching, flaking, and skin irritation.
| Pictograms : | ![]() ![]() ![]() |
| Hazard Statements : | H301+H311+H331: Toxic if swallowed, in contact with skin, or if inhaled |
| Precautionary statements : | P260: Do not breathe dust/fume/gas/mist/vapors/spray P264: Wash … thoroughly after handling. P273: Avoid release to the environment. P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P391: Collect spillage. P403+P233: Store in a well-ventilated place. Keep the container tightly closed. P501 Dispose of contents/container to industrial combustion plant. |
- Symptoms like rash, itching, hives, or facial swelling may occur and require immediate attention.
- Burning, itching, crusting, or peeling of the treated skin may indicate a more serious reaction.
- Temporary changes such as hair color/texture changes, mild hair loss, or minor skin irritation are common and usually not serious, but should be monitored if they persist.
What is Selenium Sulfide?
Selenium sulfide also known as Selenium disulfide is an anti-fungal agent with keratolytic properties. It’s a chemical compound that helps in curing various skin infections including fungal & yeast infections, by inhibiting the growth of these organisms.

CAS No.: 7488-56-4
Synonyms: selenosulfide, Selenium sulphide, Selensulfid, Selenium sulfide red powder, selenenyl sulfide, Selenium Sulfide USP.
Properties of Selenium Sulfide
| Physical Properties | |
| Chemical formula | SSe |
| IUPAC Name | Selenium disulfide |
| Molecular weight | 111.04 g/mol |
| Solubility | In carbon disulfide |
| Insoluble | In H2O & Organic solvents/td> |
| Density | 3.0g/cm3 at 32°C |
| Chemical Properties | |
| Color | Bright orange or yellow |
| State | Powder |
| Melting point | 231.9°F (111°C) |
| Boiling Point | 224-246°F |
| Specific gravity | 3.056 at 32°F |
Applications of Selenium Sulfide
- Medical Diagnosis:
Seborrheic Dermatitis – Selenium sulfide 2.5% shampoo works by reducing the production of sebum and inhibits the growth of fungi, improving the symptoms of seborrheic dermatitis and dandruff.Yeast dermatitis – Selenium sulfide is effective in treating yeast dermatitis by inhibiting the growth of yeast on the skin. It reduces symptoms like redness, itching, and flaking, providing relief and improving skin condition with regular use.
Tinea versicolor – Selenium sulfide usp 2.5 lotion helps in the treatment of tinea versicolor, a fungal infection that causes discolored patches on the skin, by reducing fungal growth it helps to restore the skin’s normal color and texture with consistent application.
Jock Itch – Selenium sulfide can be used to treat Jock itch, a fungal infection in the groin area as it inhibits the fungal growth and relieves symptoms like itching and irritation.
- Veterinary Medicine: Selenium sulfide is used in veterinary medicine for the primary treatment of fungal infections like ringworm in animals. It helps to reduce itching, flaking, and skin irritation.
| Pictograms : | ![]() ![]() ![]() |
| Hazard Statements : | H301+H311+H331: Toxic if swallowed, in contact with skin, or if inhaled |
| Precautionary statements : | P260: Do not breathe dust/fume/gas/mist/vapors/spray P264: Wash … thoroughly after handling. P273: Avoid release to the environment. P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P391: Collect spillage. P403+P233: Store in a well-ventilated place. Keep the container tightly closed. P501 Dispose of contents/container to industrial combustion plant. |
- Symptoms like rash, itching, hives, or facial swelling may occur and require immediate attention.
- Burning, itching, crusting, or peeling of the treated skin may indicate a more serious reaction.
- Temporary changes such as hair color/texture changes, mild hair loss, or minor skin irritation are common and usually not serious, but should be monitored if they persist.
FAQ's
Selenium sulfide is primarily used to treat yeast and fungal skin infections.
Selenium sulfide is an anti-fungal agent as it helps in the treatment of seborrheic dermatitis, a condition that causes dry, flaky, and itchy skin.
Selenium sulfide may cause irritation, inflammation, and dryness on scalp areas not affected by dandruff. This can potentially disrupt the normal function of the scalp and hair follicles.
 You can apply selenium sulfide to the affected skin and face, avoiding contact with eyes, nose, and open wounds. Do not leave it on the skin for too long, and consult a doctor if side effects occur.
Head & Shoulders Clinical Strength Shampoo uses selenium sulfide to effectively treat severe dandruff and itchy scalp caused by seborrheic dermatitis.
The 2.5% selenium sulfide lotion is available by prescription only, while the 1% strength (like Selsun Blue) can be purchased over the counter.



