
Sodium Octyl Sulfate is an anionic surfactant also known as sodium n-octyl sulfate with the chemical formula C₈H₁₇NaO₄S. Its structure contains an eight-carbon hydrophobic chain connected to a hydrophilic sulfate group giving it characteristic surface-active and ion-pairing properties. In biochemical research, the compound is valuable for investigating protein-surfactant interactions, including albumin enrichment and changes in protein structure or enzyme activity. It is also studied in mixed surfactant systems to understand interactions between anionic and cationic surface-active compounds.

CAS No.: 142-31-4
Synonyms: Sodium octyl sulphate.
| Physical Properties | |
| Chemical formula | C8H17NaO4S |
| IUPAC Name | sodium octyl sulfate |
| Molecular weight | 232.28 g/mol |
| Solubility | Soluble in water |
| Density | 1.04 g/cm³ |
| Appearance | White to Light yellow powder to crystal |
| Storage | Store at room temperature |
| Chemical Properties | |
| Color | White |
| Physical State | Solid |
| Melting Point | 195 °C |
| Ph | 6-8 (20 °C, 10 g/L in H2O) |
| Odor | Characteristic odor |
| Pictograms : | ![]() |
| Hazard Statements : | H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary Statements: | P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P280: Wear protective gloves, protective clothing, eye protection, face protection. P302+P352: IF ON SKIN: Wash with plenty of water. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Sodium Octyl Sulfate is an anionic surfactant also known as sodium n-octyl sulfate with the chemical formula C₈H₁₇NaO₄S. Its structure contains an eight-carbon hydrophobic chain connected to a hydrophilic sulfate group giving it characteristic surface-active and ion-pairing properties. In biochemical research, the compound is valuable for investigating protein-surfactant interactions, including albumin enrichment and changes in protein structure or enzyme activity. It is also studied in mixed surfactant systems to understand interactions between anionic and cationic surface-active compounds.

CAS No.: 142-31-4
Synonyms: Sodium octyl sulphate.
| Physical Properties | |
| Chemical formula | C8H17NaO4S |
| IUPAC Name | sodium octyl sulfate |
| Molecular weight | 232.28 g/mol |
| Solubility | Soluble in water |
| Density | 1.04 g/cm³ |
| Appearance | White to Light yellow powder to crystal |
| Storage | Store at room temperature |
| Chemical Properties | |
| Color | White |
| Physical State | Solid |
| Melting Point | 195 °C |
| Ph | 6-8 (20 °C, 10 g/L in H2O) |
| Odor | Characteristic odor |
| Pictograms : | ![]() |
| Hazard Statements : | H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. |
| Precautionary Statements: | P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P280: Wear protective gloves, protective clothing, eye protection, face protection. P302+P352: IF ON SKIN: Wash with plenty of water. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
Sodium octyl sulfate is used as an anionic surfactant, detergent and ion-pairing reagent. In research laboratories, it is particularly useful in HPLC, albumin enrichment studies, surfactant interaction research and investigations involving proteins and biological membranes.
Sodium Octyl Sulfate is an anionic surfactant, also known as Octyl Sulfate Sodium Salt or Sodium Capryl Sulfate, widely used as a detergent, wetting agent, and laboratory reagent.
Sodium Octyl Sulfate and Sodium lauryl sulfate are not the same compound. They are distinct anionic surfactants with different carbon chain lengths and chemical formulas. Sodium octyl sulfate has an eight-carbon chain, while sodium lauryl sulfate has a twelve-carbon chain.
Sodium Octyl Sulfate is used as an ion-pairing reagent in HPLC, where it interacts with positively charged analytes to form ion pairs, increasing their retention on reversed-phase columns and improving chromatographic separation.