Methylthymol Blue sodium salt is a chelating agent and metal chromogenic indicator. It exhibits a distinct color change when interacting with certain metal cations. It is also a water-soluble, thymol-containing organic dye that changes with pH, from yellow in acidic conditions to blue in alkaline conditions. The dye is characterized by its sensitivity, stability and distinct chromogenic behavior. Methylthymol Blue sodium salt is also known as a histological and hematological stain and has a reported absorption maximum (λmax) of 438 nm.
CAS No.: 1945-77-3
Synonyms: Methylthymol blue W/S, Methylthymol blue sodium.
| Physical Properties | |
| Chemical formula | C37H40N2Na4O13S |
| IUPAC Name | tetrasodium;2-[[5-[3-[3-[[bis(carboxylatomethyl)amino]methyl]-4-hydroxy-2 -methyl-5-propan-2-ylphenyl]-1,1-dioxo-2,1λ6-benzoxathiol-3-yl]-2-hydroxy-6 -methyl-3-propan-2-ylphenyl]methyl-(carboxylatomethyl)amino]acetate |
| Molecular weight | 844.7 g/mol |
| Solubility | Soluble in water |
| Appearance | Dark green to red-brown to black |
| Storage | Store at room temperature |
| Chemical Properties | |
| Color | Black |
| Physical State | Solid |
| Ph | 6.2 (20 °C, 10 g/L in H2O) |
| λmax | 438 nm |
| Odor | Odorless or slight nitric acid odor |
pH Indicator and Quality Testing- Methylthymol Blue sodium salt is used as a visual pH indicator for monitoring acidity and alkalinity in solutions. Its color response also supports pH monitoring during food processing and quality-control testing.
Complexometric and Metal Ion Analysis- It is used in complexometric procedures for the determination of metal ions including calcium and magnesium.
Sulfate Determination- It is used as an analytical reagent for the determination of sulfate in aqueous samples, including rainwater.
Histological and Hematological Staining- The dye serves as a biological staining reagent in histological and hematological laboratory studies.
Biochemical Assays- It is applied in biochemical research for monitoring enzyme activity and metabolic processes during experimental studies.
Environmental Testing- Methylthymol Blue sodium salt is employed in environmental and water analysis for evaluating selected chemical parameters in water samples.
Colorimetric Sensor Research- Its sensitivity to changes in the surrounding chemical environment supports research and development of colorimetric sensing systems.
Educational Laboratories- It is used in laboratory experiments to demonstrate acid–base reactions, indicator behavior, chelation, and analytical chemistry principles.
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| Pictograms : |  |
| Hazard Statements : | H350: May cause cancer. H360: May damage fertility or the unborn child. H373 May cause damage to organs (Liver) through prolonged or repeated exposure. |
| Precautionary Statements: | P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P260: Do not breathe dust. P280: Wear protective gloves/ protective clothing/ eye protection/ face protection P308 + P313: IF exposed or concerned: Get medical advice/ attention. P405: Store locked up. P501: Dispose of contents/ container to an approved waste disposal plant. |
Methylthymol Blue sodium salt is a chelating agent and metal chromogenic indicator. It exhibits a distinct color change when interacting with certain metal cations. It is also a water-soluble, thymol-containing organic dye that changes with pH, from yellow in acidic conditions to blue in alkaline conditions. The dye is characterized by its sensitivity, stability and distinct chromogenic behavior. Methylthymol Blue sodium salt is also known as a histological and hematological stain and has a reported absorption maximum (λmax) of 438 nm.
CAS No.: 1945-77-3
Synonyms: Methylthymol blue W/S, Methylthymol blue sodium.
| Physical Properties | |
| Chemical formula | C37H40N2Na4O13S |
| IUPAC Name | tetrasodium;2-[[5-[3-[3-[[bis(carboxylatomethyl)amino]methyl]-4-hydroxy-2 -methyl-5-propan-2-ylphenyl]-1,1-dioxo-2,1λ6-benzoxathiol-3-yl]-2-hydroxy-6 -methyl-3-propan-2-ylphenyl]methyl-(carboxylatomethyl)amino]acetate |
| Molecular weight | 844.7 g/mol |
| Solubility | Soluble in water |
| Appearance | Dark green to red-brown to black |
| Storage | Store at room temperature |
| Chemical Properties | |
| Color | Black |
| Physical State | Solid |
| Ph | 6.2 (20 °C, 10 g/L in H2O) |
| λmax | 438 nm |
| Odor | Odorless or slight nitric acid odor |
pH Indicator and Quality Testing- Methylthymol Blue sodium salt is used as a visual pH indicator for monitoring acidity and alkalinity in solutions. Its color response also supports pH monitoring during food processing and quality-control testing.
Complexometric and Metal Ion Analysis- It is used in complexometric procedures for the determination of metal ions including calcium and magnesium.
Sulfate Determination- It is used as an analytical reagent for the determination of sulfate in aqueous samples, including rainwater.
Histological and Hematological Staining- The dye serves as a biological staining reagent in histological and hematological laboratory studies.
Biochemical Assays- It is applied in biochemical research for monitoring enzyme activity and metabolic processes during experimental studies.
Environmental Testing- Methylthymol Blue sodium salt is employed in environmental and water analysis for evaluating selected chemical parameters in water samples.
Colorimetric Sensor Research- Its sensitivity to changes in the surrounding chemical environment supports research and development of colorimetric sensing systems.
Educational Laboratories- It is used in laboratory experiments to demonstrate acid–base reactions, indicator behavior, chelation, and analytical chemistry principles.
Â
| Pictograms : | |
| Hazard Statements : | H350: May cause cancer. H360: May damage fertility or the unborn child. H373 May cause damage to organs (Liver) through prolonged or repeated exposure. |
| Precautionary Statements: | P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P260: Do not breathe dust. P280: Wear protective gloves/ protective clothing/ eye protection/ face protection P308 + P313: IF exposed or concerned: Get medical advice/ attention. P405: Store locked up. P501: Dispose of contents/ container to an approved waste disposal plant. |
Methylthymol Blue sodium salt is a water-soluble organic dye, and it is used in complexometric analysis, pH monitoring, metal-ion determination, sulfate analysis, biological staining, biochemical assays and environmental testing.
Methylthymol Blue indicates changes in pH and interactions with certain metal ions. It generally changes from yellow in acidic conditions to blue in alkaline conditions, while its color can also vary upon complexation with metal ions.
Methylthymol Blue sodium salt is a water-soluble complexometric indicator containing iminodiacetate groups that enable chelation with metal ions such as calcium and magnesium. While, thymol blue is primarily a two range pH indicator with red-yellow-blue transitions and is mostly insoluble in water.
Methylthymol Blue sodium salt is used in analytical procedures for determining sulfate in aqueous samples, including rainwater.
