Isosulfan Blue is a synthetic triarylmethane aniline dye and the 2,5-disulfonated isomer of Patent Blue, widely used in medical diagnostics and research to detect abnormalities or injuries in lymphatic vessels, particularly in lymphangiography and sentinel lymph node mapping.
CAS No.: 68238-36-8
Synonyms: Â Iso-sulphan blue, lymphazurin blue
| Properties | |
| Chemical formula | C27H31N2NaO6S2 |
| IUPAC name | sodium 2-[[4-(diethylamino)phenyl]- (4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene) methyl]benzene-1,4-disulfonate |
| Molecular weight | 566.7 g/mol |
| Solubility | Slightly soluble in alcohol, Practically insoluble in non-polar organic solvents |
| Odor | Odorless |
| Appearance | Dark bluish-green powder |
| Pictograms : |
|
| Hazard Statements : | H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation |
| Precautionary statements : | P261 Avoid breathing dust/fume/gas/mist/vapors/spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P302+P352 IF ON SKIN: Wash with plenty of soap and water. |
Isosulfan Blue is a synthetic triarylmethane aniline dye and the 2,5-disulfonated isomer of Patent Blue, widely used in medical diagnostics and research to detect abnormalities or injuries in lymphatic vessels, particularly in lymphangiography and sentinel lymph node mapping.
CAS No.: 68238-36-8
Synonyms: Â Iso-sulphan blue, lymphazurin blue
| Properties | |
| Chemical formula | C27H31N2NaO6S2 |
| IUPAC name | sodium 2-[[4-(diethylamino)phenyl]- (4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene) methyl]benzene-1,4-disulfonate |
| Molecular weight | 566.7 g/mol |
| Solubility | Slightly soluble in alcohol, Practically insoluble in non-polar organic solvents |
| Odor | Odorless |
| Appearance | Dark bluish-green powder |
| Pictograms : |
|
| Hazard Statements : | H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation |
| Precautionary statements : | P261 Avoid breathing dust/fume/gas/mist/vapors/spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P302+P352 IF ON SKIN: Wash with plenty of soap and water. |
Isosulfan Blue is primarily used for sentinel lymph node mapping and lymphatic vessel visualization during cancer surgeries.
Isosulfan blue and methylene blue are not the same compound. Isosulfan blue is a triarylmethane dye, used in the sentinel lymph node mapping, while methylene blue is a thiazine dye used in the treatment of methemoglobinemia.
Isosfulfan blue and lymphazurin are the same compound used to delineate lymphatic vessels.
Isosulfan blue is not radioactive and is used to stain lymphatic vessels and nodes to a visible blue color, and aids in the surgical identification.
