Niacinamide
What is Niacinamide?
Niacinamide is a type of vitamin B3 that has a myriad of topical and dermatological uses. It is water-soluble, that is, the body does not store it and needs a regular supply via skincare or diet. Niacinamide is commonly found in foods like eggs, fish, and meat and is also used in cosmetic products such as lotions, creams and serums.
CAS No.: 98-92-0
Synonyms: Nicotinamide, 3-Pyridinecarboxyamide, Pyridine-3-carboxyamide
Properties of Niacinamide
| Physical Properties | |
| Chemical formula | C6H6N2O |
| IUPAC name | 3-Pyridinecarboxyamide |
| Molecular weight | 122.12 g/mol |
| Solubility | Highly soluble in water |
| Odor | Odorless |
| Taste | Bitter taste |
| Density | 1.400 g/cu cm at 25 °C |
| Chemical Properties | |
| Color | White powder |
| State | Dry powder |
| Boiling point | 334° C |
| Melting point | 128 – 131° C |
| LogP | -0.37 |
| pKa | 3.35 (at 20 °C) |
Uses of Niacinamide
Strengthens skin barrier – Topical application of Niacinamide strengthens the protective layer of skin (Stratum corneum), which keeps the moisture in and irritants out, improves skin texture, regulates oil production and can reduce inflammation.
Reduces wrinkles and fine lines – Niacinamide boost collagen production, reducing fine lines and wrinkles.
Reduces inflammation – It is effective for the treatment of acne, sensitive skin and rosacea as it reduces redness and irritation.
Prevents Vitamin B3 deficiency – Vitamin B3 is essential to treat pellagra, a skin condition caused by niacin deficiency.
Side Effects of Hydroquinone
Topical Niacinamide
- Dryness and tightness
- Allergic reaction
- Itching and tingling
- Mild redness and irritation
Oral supplement side effects
- Headache
- Nausea
- Dizzines
- Stomach upset, gas and abdominal pain
| Pictograms : |
|
| Hazard Statements : | H319: Causes serious eye irritation |
| Precautionary statements : | P264: Wash hands, eyes and face thoroughly after handling. |
What is Niacinamide?
Niacinamide is a type of vitamin B3 that has a myriad of topical and dermatological uses. It is water-soluble, that is, the body does not store it and needs a regular supply via skincare or diet. Niacinamide is commonly found in foods like eggs, fish, and meat and is also used in cosmetic products such as lotions, creams and serums.
CAS No.: 98-92-0
Synonyms: Nicotinamide, 3-Pyridinecarboxyamide, Pyridine-3-carboxyamide
Properties of Niacinamide
| Physical Properties | |
| Chemical formula | C6H6N2O |
| IUPAC name | 3-Pyridinecarboxyamide |
| Molecular weight | 122.12 g/mol |
| Solubility | Highly soluble in water |
| Odor | Odorless |
| Taste | Bitter taste |
| Density | 1.400 g/cu cm at 25 °C |
| Chemical Properties | |
| Color | White powder |
| State | Dry powder |
| Boiling point | 334° C |
| Melting point | 128 – 131° C |
| LogP | -0.37 |
| pKa | 3.35 (at 20 °C) |
Uses of Niacinamide
Strengthens skin barrier – Topical application of Niacinamide strengthens the protective layer of skin (Stratum corneum), which keeps the moisture in and irritants out, improves skin texture, regulates oil production and can reduce inflammation.
Reduces wrinkles and fine lines – Niacinamide boost collagen production, reducing fine lines and wrinkles.
Reduces inflammation – It is effective for the treatment of acne, sensitive skin and rosacea as it reduces redness and irritation.
Prevents Vitamin B3 deficiency – Vitamin B3 is essential to treat pellagra, a skin condition caused by niacin deficiency.
Side Effects of Hydroquinone
Topical Niacinamide
- Dryness and tightness
- Allergic reaction
- Itching and tingling
- Mild redness and irritation
Oral supplement side effects
- Headache
- Nausea
- Dizzines
- Stomach upset, gas and abdominal pain
| Pictograms : |
|
| Hazard Statements : | H319: Causes serious eye irritation |
| Precautionary statements : | P264: Wash hands, eyes and face thoroughly after handling. |
FAQ's
Niacinamide is a multi-purpose skincare ingredient, improves hydration of the skin and can make it stronger by protecting the protective layer of the skin.
Yes, niacinamide reduces inflammation, reducing oil production, and minimizes the appearance of scars. It creates a strong barrier by boosting the skin hydration and making the skin more resilient to environmental damage.
Yes, you can combine niacinamide with vitamin C as it enhances the properties of both the ingredients when used correctly in a skincare routine.
Yes, niacinamide and retinol can be used together, they work well together as niacinamide soothes the skin, reducing the irritation sometimes caused by retinol.
